Bioactive Small Molecules
Medchemexpress LLC HY-10233 10mg Medchemexpress, Gaboxadol (hydrochloride) CAS:85118-33-8 Purity:>98%
Medchemexpress, HY-10233 10mg Gaboxadol (hydrochloride) CAS:85118-33-8 Gaboxadol hydrochloride (Lu 02-030 hydrochloride; THIP hydrochloride) is a potent agonist of the GABAA receptor and an antagonist of GABAC receptors (IC50=25 μM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit α1β2γ2 with an ED50 value of 143 µM, a full agonist efficacy at α5 subunit (ED50=28-129 µM) and a superagonist efficacy at α4β3δ (ED50=6 µM). Gaboxadol hydrochloride is a non-opioid analgesic and has hypnotic activities. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-125959 5mg Medchemexpress, Ucf-101 CAS:313649-08-0 Purity:>98%
Medchemexpress, HY-125959 5mg Ucf-101 CAS:313649-08-0 Ucf-101 is a selctive and competitive inhibitor of pro-apoptotic protease Omi/HtrA2, with an IC50 of 9.5 μM for His-Omi. Ucf-101 exhibits very little activity against various other serine proteases (IC50>200 μM). Ucf-101 has a natural red fluorescence at 543 nm that is used to monitor its ability to enter mammalian cells. Ucf-101 has a significant cardioprotective effect against MI/R injury and also has certain neuroprotective effect. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-111475 10mg Medchemexpress, Mitochondrial fusion promoter M1 CAS:219315-22-7 Purity:>98%
Medchemexpress, HY-111475 10mg Mitochondrial fusion promoter M1 CAS:219315-22-7 Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator. Mitochondrial fusion promoter M1 preserves the mitochondrial function and promotes cellular respiration. Mitochondrial fusion promoter M1 alleviates cardiac and brain damage in rats with cardiac ischemia/reperfusion injury. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-113527 100mg Medchemexpress, 3-Carbamoyl-1-methylpyridin-1-ium chloride CAS:1005-24-9 Purity:>98%
Medchemexpress, HY-113527 100mg 3-Carbamoyl-1-methylpyridin-1-ium chloride CAS:1005-24-9 3-Carbamoyl-1-methylpyridin-1-ium chloride is an endogenous metabolite. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-108355 5mg Medchemexpress, R59949 CAS:120166-69-0 Purity:>98%
Medchemexpress, HY-108355 5mg R59949 CAS:120166-69-0 R59949 is a pan diacylglycerol kinase (DGK) inhibitor with an IC50 of 300 nM. R59949 strongly inhibits the activity of type I DGK α and γ and moderately attenuates the activity of type II DGK θ and κ. R59949 activates protein kinase C (PKC) by enhancing the levels of the endogenous ligand diacyl glycerol. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-W002585 50mg Medchemexpress, O6-Benzylguanine CAS:19916-73-5 Purity:>98%
Medchemexpress, HY-W002585 50mg O6-Benzylguanine CAS:19916-73-5 O6-Benzylguanine, a guanine analog, is the DNA repair enzyme O6-alkylguanine-DNA alkyltransferase (MGMT/AGT) inhibitor. O6-Benzylguanine acts as an AGT substrate, which transfers its benzyl group to the AGT cysteine residue, thereby irreversibly inactivating AGT and preventing DNA repair. O6-Benzylguanine induces tumor cell apoptosis. Antineoplastic activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-B0320A 500mg Medchemexpress, Cromolyn (sodium) CAS:15826-37-6 Purity:>98%
Medchemexpress, HY-B0320A 500mg Cromolyn (sodium) CAS:15826-37-6 Cromolyn sodium (Disodium Cromoglycate; FPL-670) is an antiallergic drug. Cromolyn sodium is a GSK-3β inhibitor with an IC50 of 2.0 µM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-W010936 50mg Medchemexpress, Nitrobenzylthioinosine CAS:38048-32-7 Purity:>98%
Medchemexpress, HY-W010936 50mg Nitrobenzylthioinosine CAS:38048-32-7 Nitrobenzylthioinosine is an ENT1 transporter inhibitor that binds to ENT1 transporter with high affinity. Nitrobenzylthioinosine is a photoaffinity probe for adenosine uptake sites in brain. Nitrobenzylthioinosine can cross the blood-brain barrier. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N7395A 500ug Medchemexpress, Cyclic ADP-ribose (ammonium) CAS: Purity:>98%
Medchemexpress, HY-N7395A 500ug Cyclic ADP-ribose (ammonium) CAS: Cyclic ADP-ribose ammonium (cADPR ammonium) is a potent second messenger for calcium mobilization that is synthesized from NAD+ by an ADP-ribosyl cyclase. Cyclic ADP-ribose ammonium increases cytosolic calcium mainly by Ryanodine receptor-mediated release from endoplasmic reticulum and also by extracellular influx through the opening of TRPM2 channels. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-Y0921 100mL Medchemexpress, (±)-1,2-Propanediol CAS:57-55-6 Purity:>98%
Medchemexpress, HY-Y0921 100mL (±)-1,2-Propanediol CAS:57-55-6 (±)-1,2-Propanediol is an aliphatic alcohol and frequently used as an excipient in many drug formulations to increase the solubility and stability of drugs. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-W003467 100mg Medchemexpress, Rabeprazole Sulfide CAS:117977-21-6 Purity:>98%
Medchemexpress, HY-W003467 100mg Rabeprazole Sulfide CAS:117977-21-6 Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H+/K+)-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of H. pylori. Rabeprazole has the potential for various peptic diseases treatment. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-D1005 500mg Medchemexpress, Poloxamer 407 CAS:9003-11-6 Purity:>98%
Medchemexpress, HY-D1005 500mg Poloxamer 407 CAS:9003-11-6 Poloxamer 407 is a nonionic surfactant that is 100% active and relatively non-toxic to cells at low concentrations, and frequently used with dye AM esters such as Indo-1 AM, Fura-2 AM, Calcein AM, Fluo-3 AM, Fluo-4 AM, Quest Fluo-8™ AM and Quest Rhod-4™ AM, etc. to improve their water solubility. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-W017230 25mg Medchemexpress, L-Cysteinesulfinic acid (monohydrate) CAS:207121-48-0 Purity:>98%
Medchemexpress, HY-W017230 25mg L-Cysteinesulfinic acid (monohydrate) CAS:207121-48-0 L-Cysteinesulfinic acid monohydrate is a potent agonist at several rat metabotropic glutamate receptors (mGluRs) with pEC50s of 3.92, 4.6, 3.9, 2.7, 4.0, and 3.94 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical 4QuInoLN3CarboxamIde Fur 5mg
A high-affinity ligand of CB2 (Ki = 8.5 nM) with little affinity for CB1 (Ki >10,000 nM); demonstrates antinociceptive efficacy in the mouse formalin test at 1 mg/kg, an action which is blocked by a CB2-selective antagonist, AM630
Cayman Chemical ANTIBODY 13 S-HODE 100ug
13(S)-HODE is produced by incubation of linoleic acid with plant and mammalian LOs. It has been shown to inhibit the adhesion of tumor cells to the endothelium at concentrations around 1 µM,{592,880} and down regulates the expression of the IRGpIIb/IIIa receptor.{591}